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Directories (14)
Ecological Databases (1)
Gene Expression and Regulation (10)
Genome Databases (19)
Homology Detection (14)
Molecular Biology Tools (10)
Phylogenetic Analysis (10)
Protein Analysis (45)
Software (107)
Web Pages
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  Entrez Browser http://www.ncbi.nlm.nih.gov/Entrez/
Retrieves molecular biology data and bibliographic citations from the NCBI's integrated databases.
  PIR-International Protein Sequence Database http://pir.georgetown.edu
Produces a non-redundant annotated protein sequence database. PIR features integrated annotation search to support functional/structural genomics and proteomic research.
  Searching GenBank http://www.ncbi.nlm.nih.gov/Genbank/GenbankSearch.html
Text and similarity searching, provided by the National Center for Biotechnology Information (NCBI).
  Broad Institute: Software http://www.broad.mit.edu/science/software/software
Scientists at the Broad Institute have developed a range of software tools for the analysis of increasingly large genome-related datasets. These are openly available to the scientific community.
  PubCrawler http://pubcrawler.gen.tcd.ie/
An online service for periodically performing predefined searches at NCBI, reporting new results by email or on the web.
  Center Structural Biology: Programs and Tools http://www.csb.yale.edu
User guides and worked examples for software applications in structural and molecular biology - from Yale Univ.
  http://www.thebiogrid.org/ http://www.thebiogrid.org/
Database of genetic and physical interactions. It contains interaction data from many sources, including several genome/proteome-wide studies, the MIPS database, and BIND.
  Scansite http://scansite.mit.edu/
Scansite searches for motifs within proteins that are likely to be phosphorylated by specific protein kinases or bind to domains such as SH2 domains, 14-3-3 domains or PDZ domains.
  SA National Bioinformatics Institute http://www.sanbi.ac.za/
SANBI aims to bring genome information, computational biology, and analytical tools to the South African research community. Hosts SA National EMBNet Node, provides links to Sequence Retrieval System (SRS), GeneKraal, and TB Genomes Analysis Server. Research in Sequence Tag Alignment and Consensus Knowledgebase (STACK). Databases include BLAST search in Mycobacterium genome.
  Silva: Comprehensive Ribosomal RNA Databases http://www.arb-silva.de
The provided databases comprise SSU and LSU sequences of all three domains. Online search and alignment tools are available and the results can be exported in ARB and FASTA format.
  Center for Biological Sequence Analysis http://www.cbs.dtu.dk/services/
Offers more than 30 online services for DNA and protein bioinformatics analysis.
  Information Génomique et Structurale (CNRS) http://igs-server.cnrs-mrs.fr
Online services including T-Coffee, El-Nemo, Casper and FeeBack.
  Biomolecular Interaction Network Database (BIND) http://bind.ca
BIND is a database designed to store full descriptions of interactions, molecular complexes and pathways.
  ParAlign http://www.paralign.org/
Service using the ParAlign algorithm to compare genetic sequences. Apparently it is as fast as BLAST and as sensitive as Smith-Waterman.
  NIH BioInformatics and Molecular Analysis Section http://bimas.dcrt.nih.gov
Numerous computational tools and resources to unite advances in biology with those in computers, informatics, and networking for the genomic and genetic analysis fields of BioInformatics; division of the Computational Bioscience and Engineering Lab at the Center for Information Technology.
  BioModels Database http://www.ebi.ac.uk/biomodels/
Resource for storing, searching and retrieving published mathematical models of biological interests. Models present in BioModels Database are annotated and linked to relevant data resources, such as publications, databases of compounds and pathways, controlled vocabularies, etc.
  Ligand-Gated Ion Channel Database http://www.ebi.ac.uk/compneur-srv/LGICdb/LGICdb.php
LGICdb is a curated repository of genes coding for subunits of Ligand-Gated Ion Channels.
  Bioverse http://bioverse.compbio.washington.edu
Provides a framework for exploring the relationships among the molecular, genomic, proteomic, systems, and organismal worlds.
  BioMolecular Engineering Research Center http://bmerc-www.bu.edu/index.html
Tools and methods for computational biology. Working on secondary protein structure prediction, providing reliable profiles, and developing new ways to study molecular biology through bioinformatics.
  Geneva Bioinformatics (GeneBio) S.A. http://www.genebio.com/
GeneBio provides proteomics software tools and databases including SWISS-PROT, PROSITE, SWISS-2DPAGE and Melanie. We also offer a secure version of ExPASy molecular biology web server.
  IBM Bioinformatics Group - Tools & Content http://cbcsrv.watson.ibm.com/Tspd.html
Several genomics and proteomics tools, including multiple alignments, gene expression analysis, tandem repeat and motif discovery.
  JustBio: Online Tool Set http://www.justbio.com/tools.php
A Suite of Online tools for analysis of DNA/RNA, Proteins, and Arrays.
  Molecular Interactions Database (MINT) http://cbm.bio.uniroma2.it/mint/
MINT is a database designed to store functional interactions between biological molecules (proteins, RNA, DNA).
  http://www.gene-regulation.com/ http://www.gene-regulation.com/
The focus of the GBF project "Molecular Bioinformatics of Gene Regulation" are regulatory genomic signals and regions that govern transcriptional control based on TRANSFAC - The Transcription Factor Database. It compiles data about gene regulatory DNA sequences and protein factors binding to and acting through them.
  Bacterial Identification http://pbil.univ-lyon1.fr/bibi/query.php
Service for the identification of bacteria and fungi sequences by sequence alignment.
  http://mobyle.pasteur.fr http://mobyle.pasteur.fr
Framework and web portal specifically designed for the integration of bioinformatics software and databanks. Provides a tutorial and an interactive guided tour.
  http://bimas.dcrt.nih.gov/molbio/readseq/ http://bimas.dcrt.nih.gov/molbio/readseq/
Converts amino acid and nucleotide sequence data formats including FASTA, GenBank, Phylip and others.
  My Genomics Resource Centre http://www.mgrc.com.my
A Malaysian Genomics toolset for high-throughput analysis of biological data. Must register to use.
  Genepop on the Web http://wbiomed.curtin.edu.au/genepop/
Online version of the program for populational genetics.
  CUBIC: Columbia University Bioinformatics Center http://cubic.bioc.columbia.edu/
Features PredictProtein service for sequence analysis and protein structure prediction, META for single-page interface to validated sequence analysis, PredictNLS for prediction and analysis of nuclear localization signals, EVA for evaluation of automatic protein structure prediction servers, and DSSPcont for continuous assignment of protein secondary structure.
  GenOuest Bioinformatics Platform http://genouest.org
Provides a complete set of bioinformatics tools and public databanks updated daily, and a range of links to seminars, training courses and platform news.
  Molecular Informatics Resource for the Analysis of Gene Expression http://www.ifti.org/
Information methodologies, tools, and technologies relating to the study of gene expression and signal transduction from the Institute for Transcriptional Informatics.
  http://mulan.dcode.org/ http://mulan.dcode.org/
Performs single-coverage local multiple DNA sequence alignments of finished and draft-quality genome sequences. It also provides with an option to predict transcription factor binding sites evolutionarily conserved across multiple species.
  Gene and Protein Synonyms DataBase http://biomint.pharmadm.com
Free service for retrieving all synonyms for a given gene or protein name.
  Canadian Bioinformatics Help Desk http://gchelpdesk.ualberta.ca
We provide bioinformatics support, services, servers, and software to Canadian researchers.
  ProteinLounge http://www.proteinlounge.com
Bioinformatics portal which integrates protein information and many databases and research tools useful for researchers and students. Subscription based service.
  http://www.ihop-net.org/UniPub/iHOP/ http://www.ihop-net.org/UniPub/iHOP/
Uses the network of genes and proteins as a natural way of accessing the millions of biomedical abstracts in PubMed.
  http://www.pandora.cs.huji.ac.il http://www.pandora.cs.huji.ac.il
Protein ANnotation Diagram ORiented Analysis service that extracts biological information from user supplied sequences.
  PlasMapper http://wishart.biology.ualberta.ca/PlasMapper/index.html
Online service to generate annotated plasmid maps up to 20 kbp. Outputs in PNG, JPG, SVG or SVGZ format.
  TFM Explorer http://bioinfo.lifl.fr/TFM-Explorer/
Scans sequences for potential Transcription Factor binding sites using Patser and TRANSFAC.
  DBD: Transcription Factor Prediction Database http://dbd.mrc-lmb.cam.ac.uk
DBD is a database of predicted transcription factors in completely sequenced genomes. The predicted transcription factors all contain assignments to sequence specific DNA-binding domain families.
  UEA Plant sRNA Toolkit http://srna-tools.cmp.uea.ac.uk
A suite of tools for the analysis of sRNA datasets from high-throughput sequencing experiments.
  ProPred-I http://www.imtech.res.in/raghava/propred1
An online service for predicting MHC binding regions in antigens. It also offers the proteasomal and immunoproteasomal filters to improve the applicability of results.
  http://www.webact.org http://www.webact.org
A database of sequence comparisons between all publicly available prokaryotic genome sequences, allowing the on-line visualisation of comparisons between up to five genomic sequences, using the Artemis Comparison Tool. User can perform their comparisons on their own data.
  Docking Server http://www.dockingserver.com
Provides an internet service that calculates the site, geometry and energy of small molecules interacting with proteins.
  YMF - DNA Motif Finding Program http://abstract.cs.washington.edu/~saurabh/YMFWeb/YMFInput.pl
Finds novel transcription factor binding sites by searching for over-represented (most significant motifs) motifs in DNA sequences.
  Advanced Genetics Wizard http://www.geneticswizard.com
Online program that calculates the distribution of offspring genotypes from dominant, codominant and recessive gene crosses, for up to 6 genes.
  LongTrace DNA Sequencing Service https://www.nucleics.com/longtrace/
A commercial service for improving the read length and quality of ABI 3730, 3130 and 3100 DNA sequencing traces. Works via reprocessing of the raw peak data before re-base calling. A free trial is provided.
  Verbumculus Genetic Sequence Analyzer http://www.cs.ucr.edu/~stelo/Verbumculus/
An interesting tool to discover and visualize over- or under-represented words in genetic sequences. Requires Java support in browser. Also available as a downloadable program.
  Transterm http://uther.otago.ac.nz/Transterm.html
Interactive database of mRNA regions and motifs from all species and genomes. Users can browse the pre-computed data tables, search the sequence databases or search their own sequences.
  QGRS Mapper http://bioinformatics.ramapo.edu/QGRS/
Generates information on composition and distribution of putative Quadruplex forming G-Rich Sequences (QGRS) in nucleotide sequences and NCBI genes.
  Splice Center http://www.tigerteamconsulting.com/SpliceCenter/SpliceOverview.jsp
Suite of user-friendly tools that evaluate the impact of gene splicing variation on specific molecular biology techniques.
  Splice Miner http://www.tigerteamconsulting.com/SpliceMiner/intro.jsp
Tool for querying Evidence Viewer Database (EVDB), a comprehensive, non-redundant collection of splice variant data for human genes.
  Your Lab Data http://www.yourlabdata.com/
A free web-based Laboratory Information Management System (LIMS), aimed at a typical small molecular biology laboratory allowing members to have their own private forum, events, Electronic Lab Notebook (ELN) and a LIMS area.
  InstaSeq http://bioinformatics.georgetown.edu/InstaSeq.htm
Google-based search engine for DNA, RNA or Protein sequences.
  Functional Human Gene Network http://www.genenetwork.nl
Consolidates evidence for gene-gene interactions from HPRD, BIND, Reactome, KEGG, GO, microarray co-expression and Y2H experiments. Beautiful site design.
  PathCase: Pathways Database System http://nashua.case.edu/pathwaysweb/
An integrated software system for storing, managing, analyzing, and querying metabolic pathways at genetic, molecular, biochemical and organism levels.
  http://bioinfo.lifl.fr/carnac/ http://bioinfo.lifl.fr/carnac/
A free software tool for analysing the hypothetical secondary structure of a family of homologous RNA.
  Systems Biology of Photosynthesis http://www.e-photosynthesis.org
Open web platform for modeling and reverse engineering of photosynthetic dynamism.
  http://ergo.integratedgenomics.com/ERGO/ http://ergo.integratedgenomics.com/ERGO/
Online service integrating biological data from genomics, biochemistry, genetics and high-throughput expression profiling, to achieve a pattern-based analysis of genes and genomes.
  gp2fasta http://gp2fasta.ovh.org/
Converts gp files from NCBI GenPept format to fasta. Its main purpose is to create fasta files with short, but still accurate headers for sequence.
  INCBI Irish National Centre for BioInformatics http://acer.gen.tcd.ie/
Hosts Irish embnet node, Gives links to Database browsing and interrogation at SRS, European (EBI) servers, Blast server for parasite genomes (EBI), US (NCBI) servers, Protein structure prediction, PredictProtein Server in Heidelberg, Gene identification, splice sites, exons, introns and a list of gene structure prediction programs
  GenePattern http://www.genepattern.org
This platform provides over 100 methods for the analysis and visualization of gene expression, copy number, proteomic and other data. It enables biologists to add new analyses and create workflows that can be shared, edited and published.
  Gene Expression Data Analysis http://bioinformatics.upmc.edu/GE2/GEDA.html
Normalization tests for differentially expressed genes, clustering, bootstrapping, leave-one-out validation, cross-fold validation.
  Sequence Analysis (Bielefeld University Bioinformatics Server) http://bibiserv.techfak.uni-bielefeld.de/intro/seqdept.html
Collection of sequence analysis tools.
  Transcription Element Search Software (TESS) http://www.cbil.upenn.edu/cgi-bin/tess/tess
Very helpful software for locating and displaying transcription factor binding sites within DNA sequences - from the Univ. of Penn.
  Zinc Finger Tools http://www.scripps.edu/mb/barbas/zfdesign/zfdesignhome.php
Helps users design zinc finger transcription factors.
  BiNCO-wiki http://pgrc-35.ipk-gatersleben.de/pls/htmldb_pgrc/f?p=160:1:3068865960025140
Provides a collection of information on data sources for biological networks, file formats that save biological networks and software to analyze the information of these sources.
  QualTrace DNA Sequencing http://www.nucleics.com/qualtrace-dna-sequencing-demo/index.php
A free online version of the QualTrace DNA sequencing software for quality control analysis of ABI 3730 and 3730xl traces files.

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